This is the radius of the tool itself, within which the guides will be painted onto the surface.
If you paint guides onto a surface using click & drag, this setting defines how often guides will be painted onto a surface. If this setting is given a value of 10, guides will be set every 10 pixels for each mouse movement.
This is the maximum number of guides that will be set per individual click or each time guides are set (Step).
This setting defines the length of the guides that will be painted onto the surface.
This is the minimum distance between set guides.
If this setting is active, newly created guides will be interpolated between existing guides.
Use this setting to adjust the degree of interpolation of the newly painted Guides. A value of 0% will result in no interpolation (Guides will stand completely perpendicular to the surface). A value of 100% will result in complete interpolation. Setting the value to 100% is not advisable since Guides could result that penetrate the surface - something that should be avoided. A value of around 70% will deliver the best results.
If you use a graphics tablet, use Pressure to define which setting (None, Radius, Length, Count) should be affected by the pen.